Mirjana Antonijevic (ESR6) wins best poster at GP2A Medicinal Chemistry Conference

Mirjana Antonijevic (ESR 6) and Prof. Christophe Rochais represented the EuroNeurotrophin project at the 27th Annual GP2A Medicinal Chemistry Conference, which took place at the University of Nottingham (UK) between 21st-23rd August 2019. During these three days, Mirjana presented the work she has done during her first PhD year at CERMN institute at the University of Caen Normandie. The poster presentation “In silico screening and development of small molecules neurotrophin receptors ligands” received the best poster award.

In EuroNeuroTrophin, Mirjana is working on in silico screening of UNICAEN chemical library in order to identify hit molecules as ligands for neurotrophin receptors. In silico data will be evaluated along with a high-throughput screening of the before mentioned chemical library. Selected hit molecules will be subjected to the study of hit to lead optimization, with an aim to better understand the molecular patterns involved in target-ligand interactions. Additionally, these studies will be expanded by the physicochemical optimization of the selected hit compounds. The final lead compounds will be fluorescently labeled for in vivo bioimaging studies.

We would like to congratulate Mirjana on her award and look forward to hearing more about her research.