ESR8: Canelif Yilmaz

Evaluation of small molecule neurotrophin mimetics in models of neurodegeneration and neuroinflammation

EuroNeurotrophin Research
Canelif will be investigating the anti-inflammatory effects and mechanism of action of the most potent neurotrophin mimetics, in microglia and astrocytes. She will perform tracking of the fluorescently labelled neurotrophin mimetics in mice. Furthermore, Canelif will investigate the efficacy of these molecules in vivo using cuprizone induced MS model in mice.

Host
B6: Technische Universität Dresden, Faculty of Medicine, Department of Clinical Pathobiochemistry, Germany

Supervisor
Dr. Vasileia Ismini Alexaki, Technische Universität Dresden

Scientific Background
Canelif has received her B.Sc. degree from Koç University, Istanbul, majoring in Molecular Biology, with a minor degree in Chemistry, in 2015. Following that, she has completed her M.Sc. in Neuroscience at Bilkent University, Ankara, in 2017. Her master’s research was on applications of biomimetic peptide nanofibers, aimed to improve Schwann cell myelination and neural regeneration.