ESR10: Débora Pita
Development of Human Cell-Based Models for Neurotrophic Therapeutic Testing
Débora will conduct research in building a cell-based model of human neuronal function for use in the evaluation of candidate therapeutics with neurotrophic properties. The model shall be a representation of cells with human neuronal characteristics and functionality produced by the controlled differentiation of human induced pluripotent stem cells (iPS cells). The project shall exploit existing methods for iPS differentiation into neuronal cells and shall apply know-how and proprietary technology, which can translate the neuronal model into a commercially practical screening tool.
B7: AvantiCell Science Ltd., United Kingdom
Dr. Marie-Ann Ewart, AvantiCell Science Ltd.
Débora has obtained her Bachelor degree in Biotechnology at University of Vic – Central University of Catalunya, Spain, and her interuniversity Master in Neurosciences at University of A Coruña, University of Santiago de Compostela and University of Vigo, Spain; where she obtained the specialty in Molecular and Cellular Neuroscience. For her MSc project she started a project related with Parkinson’s disease (PD), at Department of Morphological Sciences at the University of Santiago de Compostela, Spain. At the end of her placement, she exposed her Master’s Thesis in the “XIII days for young researchers in Neuroscience” in Santiago de Compostela.
The project involved the differentiation of the N27 cell line into dopaminergic neurons to use them as a tool for the study of PD. She also characterized the presence of the Renin-Angiotensin system (RAS), included the new components of the protecting arm of the RAS as Mas Receptor.
In November 2019, Débora joined the EuroNeurotrophin Network at AvantiCell Science Ltd, Scotland, UK.