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EURONEUROTROPHIN
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      • Ka Wan Li
      • Dame Pamela Shaw
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      • ESR1: Daniele Narducci
      • ESR2: Alessia Latorrata
      • ESR3: Athanasios-Alexandros Tsengenes
      • ESR4: Christina Athanasiou
      • ESR5: Federica Carucci
      • ESR6: Mirjana Antonijević
      • ESR7: Paolo Giaccio
      • ESR8: Canelif Yilmaz
      • ESR9: Ana Aragón
      • ESR10: Débora Pita
      • ESR11: Thanasis Rogdakis
      • ESR12: Desponia Charou
      • ESR13: Evangelia Thanou
      • ESR14: Marco Destro
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International Conference on “Neurotrophic Factors and Neurodegenerative Disorders; Current Advances and Future Perspectives”

Virtual │ August 27th-29th 2021
​
Heraklion, Crete, Greece
  • Overview
  • Programme
  •  Speakers
  • ESRs
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We kindly invite you to the conference entitled “Neurotrophic Factors and Neurodegenerative Disorders; Current Advances and Future Perspectives” that will be organised in the context of the “EuroNeurotrophin” project by FORTH, in Crete, on August 27th-29th 2021.

The Conference will be delivered as a virtual event and registration is free of charge.
Neurodegenerative diseases (ND), like Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis and motor neuron disease, are on the rise worldwide.  Alzheimer’s disease alone affects 36 million people in the world and 7 million in Europe. The economic burden for ND exceeds 724 billion € and it will become a trillion euros by 2019. Currently, there is no cure for any ND and most of the available drugs fail to tackle ND pathogenesis.

Neurotrophins are a family of closely related secreted proteins that have been shown to control a number of aspects of survival, development and function of neurons both in the central and the peripheral nervous systems.

Preclinical studies point to the therapeutic potential of neurotrophins in preventing or slowing the progression of ND. Thus, neurotrophins have been proposed as therapeutic agents for neurodegenerative diseases.

However, the poor pharmacokinetic properties of neurotrophins, mainly because of their sensitivity to proteolysis, restricted penetration of the blood–brain barrier, and limited ability to diffuse in tissues, render their use as drugs prohibitive.

The EuroNeurotrophin project aims to address the major limitations of neurotrophins by developing novel small molecule, neurotrophin mimetics  with favourable profiles of stability, tissue penetration and targeted biological actions.

The EuroNeurotrophin project is the first European consortium to study small molecule neurotrophin mimetics (synthetic or natural) in depth, use them as molecular probes to interrogate neurotrophins, and emphasise their clinical translation.
​
We look forward to seeing you online in August!

Session topics
  • In silico and structural biology studies of neurotrophin receptors
  • Medicinal Chemistry-Neurotrophin Mimetics
  • Neurotrophins and neurological diseases: from molecular mechanisms to  therapeutic potential
  • The neurogenic potential of neurotrophins
  • Novel therapeutic approaches for neurodegenerative diseases
  • Development of novel technologies for neurotrophin testing
  • Friday
  • Saturday
  • Sunday
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Keynote Speakers
  • Prof. Dame Pamela J. Shaw, University of Sheffield & Sheffield Institute for Translational Neuroscience (SITraN)
    Title: "Amyotrophic lateral sclerosis: A model neurodegenerative disorder poised for translation"
  • Prof. Ilpo Vattulainen, University of Helsinki
    ​Title: ​"What biomolecular simulations can offer? Understanding and controlling the function of neuroreceptors at the level of a single molecule"
  • Prof. Didier Rognan, Université de Strasbourg
    Title: "TrkB positive allosteric modulators: First-in class BDNF potentiators for the treatment of neurodegenerative diseases"
  • Prof. Frank Longo, Stanford University
    Title:  “Early Steps and Ongoing Progress in Creating and Applying Small-Molecule Modulators of Neurotrophin Receptors
  • Prof. Eero Castren, University of Helsinki
    Title: “BDNF receptor TrkB as the antidepressant target”
  • Prof. Carlos F. Ibáñez, IDG/McGovern at Peking University & Chinese Institute for Brain Research & Karolinska Institute 
    Title: "Genetic dissection of death receptor p75NTR signaling in a mouse model of Alzheimer’s Disease”
  • Dr Evgenia Saltas, Netherlands Institute for Neuroscience
    Title: “Boosting adult hippocampal neurogenesis in Alzheimer’s disease”
  • Prof. Clive Svendsen, Cedars Sinai Medical Center 
    Title: "Stem cells secreting GDNF for the treatment of Parkinson’s Disease and ALS"
  • Prof. Uri Saragovi, McGill University
    Title: “Complementary neuroprotecitve and anti-neurotoxic strategies: targets and mechanisms”
  • Dr. Ioannis Sotiropoulos, NCSR "Demokritos" Greece
    Title: “Tau protein and Neuronal (mal)plasticity in Stress and Alzheimer disease pathologies”

Invited Lecture
  • Dr Iosif Pediaditakis (Emulate, USA)
    Title "Microengineered Human Brain-Chip for Disease Modeling Applications"
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Prof. Eero Castren 
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Prof. Carlos F. Ibáñez
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Prof. Frank Longo 
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Dr Iosif Pediaditakis
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Prof. Didier Rognan
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Dr Evgenia Saltas 
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Prof. Uri Saragovi 
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Prof. Dame Pamela J. Shaw
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Dr. Ioannis Sotiropoulos
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Prof. Clive Svendsen 
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Prof. Ilpo Vattulainen
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ESR1: Daniele Narducci
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ESR2: Alessia Latorrata
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ESR3: Athanasios-Alexandros Tsengenes
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ESR4: Christina Athanasiou
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ESR5: Federica Carucci
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ESR6: Mirjana Antonijević
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ESR7: Paolo Giaccio
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ESR8: Canelif Yilmaz
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ESR9: Ana Aragón
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ESR10: Débora Pita
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ESR11: Thanasis Rogdakis
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ESR12: Despoina Charou
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ESR13: Evangelia Thanou
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ESR14: Marco Destro

Registration is now closed

Deadline  Registration: 25 August 2021

Host

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Foundation for Research and Technology Hellas​,  Greece
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National Hellenic Research Foundation​, Greece

Organisers

Prof. Ioannis Charalampopoulos
Foundation for Research and Technology Hellas, Greece
Institute of Molecular Biology and Biotechnology
charalampn@uoc.gr 

Dr. Theodora Calogeropoulou
​Research Director
Chairman of the Scientific Council of ICB 
Institute of Chemical Biology
​National Hellenic Research Foundation
tcalog@eie.gr
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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 765704
Disclaimer | Member Area
© accelopment Schweiz 2019. ALL RIGHTS RESERVED.
  • Project
    • Overview
    • Research >
      • Work Packages
      • Individual Research Projects
    • Governance
  • Network
    • Beneficiaries
    • Partner Organisations
  • People
    • Supervisors >
      • Theodora Calogeropoulou
      • Rebecca Wade
      • Stefano Mangani
      • Christophe Rochais
      • Vasileios Roussis
      • Vasileia Ismini Alexaki
      • Achilleas Gravanis
      • Ka Wan Li
      • Dame Pamela Shaw
    • Early Stage Researchers >
      • ESR1: Daniele Narducci
      • ESR2: Alessia Latorrata
      • ESR3: Athanasios-Alexandros Tsengenes
      • ESR4: Christina Athanasiou
      • ESR5: Federica Carucci
      • ESR6: Mirjana Antonijević
      • ESR7: Paolo Giaccio
      • ESR8: Canelif Yilmaz
      • ESR9: Ana Aragón
      • ESR10: Débora Pita
      • ESR11: Thanasis Rogdakis
      • ESR12: Desponia Charou
      • ESR13: Evangelia Thanou
      • ESR14: Marco Destro
    • Scientific Advisory Board
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    • Approach
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      • 3rd Network Week
  • Publications
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    • Events
    • Public Engagement
    • Results
    • Conference
    • Newsletter >
      • January 2021
      • April 2021
      • December 2021
  • News
  • Job Openings
    • Vacancies
    • Submit your application
  • Contact