ESR11: Thanasis Rogdakis
Evaluation of mirconeurotrophins activity on neurotrophin receptors and their role in signalling in invitro and in vivo neurodegenerative conditions, such as Alzheimer's Diesase.
EuroNeurotrophin Research
Novel synthetic or naturally derived microneurotrophins will be tested for their ability to activate neurotrophin receptors. Compounds that present favourable pharmacokinetic profiles will be further studied in Alzheimer’s Disease models in vitro and in vivo. Host B8: Foundation for Research and Technology Hellas, Institute of Molecular Biology and Biotechnology, Greece Supervisor Prof. Achilleas Gravanis, Foundation for Research and Technology Hellas Scientific Background After graduating for University of Athens, Biology Department Thanasis joined King’s College London for an MSc in Neuroscience. For his master thesis he studied the role of ErbB4 and its spatial and temporal expression in neocortical interneurons. For the past two years before joining EuroNeurotrophin Thanasis was working at UCL investigating synapse function with a particular focus on Wnt signalling in AD models in vitro and in vivo. |