Results

In EuroNeurotrophin, we will disseminate our results mainly via scientific publications and conference presentations. However, we will publish articles in magazines and newspapers, and document our progress in reports to the European Commission.

We will update our list of contributions to publications, presentations and received media coverage on a regular basis over the course of the project.

Presentations

• 09-10.09.2021 | Virtual | NHRF
  EFMC-YMSC 2021, 8th EFMC Young Medicinal Chemists’ Symposium.
  Alessia Latorrata (ESR2) oral presentation, Neuroprotective, Neurotrophic and Anti-Inflammatory Activity of New Synthetic Dhea Neurotrophin Mimetic Derivatives.
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• 27-29.08.2021 | Hybrid event, Heraklion, Crete, Greece | FORTH
  International Conference on “Neurotrophic Factors and Neurodegenerative Disorders; Current Advances and Future Perspectives” organised by FORTH and NHRF on behalf of the EuroNeurotrophin project. Each ESR presented during the event.
  
  
• 25-27.08.2021 | Virtual | UNICAEN
  29th Annual GP2A Medicinal Chemistry Conference, presentation by Mirjana Antonijevic (ESR6) “All for one and one for all, design and synthesis of molecules with neuronal differentiation properties”.
  Conference proceedings published on 07.12.2021, 29th Annual GP2A Medicinal Chemistry Conference. Pharmaceuticals, 14(12), 1278. https://www.mdpi.com/1424-8247/14/12/1278
  
  
• 14.05.2021 | Novartis Hellas (virtual) | NKUA
  Participation to a Workshop as part of the EurNeurotrophin Learning Scenarios “Career Path in the Pharmaceutical Industry”
  
  
• 10.05.2021 and 17.05.2021 | NHRF (virtual) | NKUA
  Participation to a Workshop as part of the EurNeurotrophin Learning Scenarios “PK/Biopharmaceutics webinar” Presentation by Dr. Katsila
  
  
• 23-24.04.2021 | Virtual | HITS
  Workshop on Computer Simulation and Theory of Macromolecules 2021
  Participation and poster presentations: Alexandros Tsengenes (ESR3) “Molecular Dynamics Simulations of the p75 Neurotrophin Receptor Transmembrane Domain” and Christina Athanasiou (ESR4) “Probing the Transmembrane Dimerization Interface of the TrkA and TrkB Receptors”
  
  
• 31.03.2021 | Heidelberg University | HITS
  Lecture, Prof. Wade gave a lecture in the Molecular Bioscience Masters students at Heidelberg University.
  
  
• 24.03.2021 | Virtual | VUA
  Pitch Event, Cell-Based Model for Neurotrophic Therapeutic Testing
  
  
• 17-19.03.2021 | USDF (virtual) | NKUA
  ​Participation to a Workshop as part of the EurNeurotrophin Learning Scenarios “Skills in Translational Neuroscience”
  
  
• 25-27.02.2021 |  Virtual | NHRF 
  18th Hellenic Symposium on Medicinal Chemistry (HSMC-18)
  Presentation by Alessia Latorrata (ESR2) “Neurotrophic, Neuroprotective and Anti-Inflammatory activity of new synthetic DHEA 17-spiro-cyclopropyl derivatives.
  
  
• 22-26.02.2021 | Virtual | HITS
  65th Biophysical Society Annual Meeting
  Prof. Wade presented EuroNeurotrophin work and the posters of the two ESRs during her talk in a session that she chaired ESR3 and ESR4 participated and presented posters in the conference.
  
  
• 11.02.2021 | Virtual | VUA
  Pitch event, BNN27 treatment effects in 5xFAD mice: an update & A proteomic approach to study tau in the AD brain
  
  
• 11-12.02.2021 | Virtual | UNICAEN
  28th YRFM -Young Research Fellows Meeting
  Presentation by Mirjana Antonijevic (ESR6) “Discovery of an allosteric pocket network of the TrkB neurotrophin receptor, a promising target in the development of new ligands”


• 16.12.2020 | 5th Drug Discovery Day | UNICAEN
  Organised by the University of Lille, Mirjana Antonijević (ESR6) had an oral presentation entitled: " Development of small molecules neurotrophin mimetics, an emerging strategy in the treatment of neurodegenerative disorders".
  
  
• 27.-28.11.2020 | Virtual | UNICAEN
  Normandy Doctoral School of Chemistry, Presentation on Multi-target neurotrophin receptors ligands, an emerging strategy in the treatment of neurodegenerative diseases by Mirjana Antonijević (ESR6), won best oral communication prize.
  
  
• 26.11.2020 | Virtual | VUA
  Pitch event, Molecular and Cellular Neurobiology Department regular meeting, Débora Pita (ESR 10) gave a presentation entitled “Cell-Based Model for Neurotrophic Therapeutic Testing”.
  
  
• 17.-18.11.2020 | Virtual | VUA
  Pitch event, Débora Pita (ESR 10) presented her project “In Vitro Models for Neurotrophic Therapeutic Testing”
  
  
• 18.06.2020 Pitch event | Virtual | VUA
  Molecular and Cellular Neurobiology Department regular meeting, Evangelia Thanou (ESR13) gave a presentation entitled “Proteomic analysis of 5xFAD mouse hippocampal tissue and rescue effects on AD pathology by neurotrophin administration.
  
  
• 10.04.2020 | Sheffield Medical School | USFD
  SITraN Monday seminar, Marco Destro (ESR14) gave a presentation entitled “The neuroprotective effects of neurotrophins in novel in vitro and in vivo models of Motor Neurone Disease (MND/ALS)”.
  
  
• 11.02.2020 | Pitch event | virtual | VUA
  Alzheimer’s Disease-CNCR regular meeting, Evangelia Thanou (ESR13) gave a presentation entitled “Application of functional proteomics to study Alzheimer's disease”
  
  
• 28.11.2019 | Besançon, DE | UNICAEN
  Workshop about the development of multi-target directed ligands for the treatment of Alzheimer disease.
  “Polypharmacology of 5-HTs receptors in Alzheimer's Disease: An illustration of CERMN research facilities” C. Rochais
  
  
• 22-24.07.2019 | Kloster Schöntal, DE | HITS
  DKFZ-ZMBH alliance retreat
  “Computer-Aided Drug Design of Small-Moleculeneurotrophin Mimetics” Athanasios-Alexandros Tsengenes (ESR3)
  
  
• 20.11.2019 | Paris, DE | UNICAEN
  8th meeting of the Foundation Alzheimer
  “The design of multi-target drug candidates with potential therapeutic interest against Alzheimer’s disease” C. Rochais
  
  
• 10.05.2019 | Hong Kong Baptish university, Hong Kong, ROC | VUA
  Seminar presentation on Proteomics analysis of neurodegenerative diseases Ka Wan Li
  
  
• 08.11.2018 | BioCity, Glasgow, UK | ACS
  ELRIG seminar
  "Recent developments in the design of biological 3D structures to support and drive translational research into Drug Discovery and Drug Development"
  
  
• 26-27.09.2019 | KANAL Pombidou Centre, Brussels, BE | FORTH
  Falling Walls Lab, in the context of EU Research and Innovation Days
  “Breaking the wall of dementia” Thanasis Rogdakis (ESR11)
  
  
• 05.09.2019 | Strasbourg, FR | UNICAEN
  Seminar presentation at the Université de Strassbourg
  "Application du concept de polypharmacologie au design du donécopride et d’autres MTDL" C. Rochais
  
  
• 04-06.10.2019 | IMBB – FORTH, EL, FORTH
  28th meeting of the Hellenic Society of Neuroscience Symposium (S9) “Symposium 9: Euroneurotrophin: small molecule neurotophin mimetics” organised by T. Calogeropoulou 
  ”EuroNeurotrophin: A European training network for the discovery of neurotrophins small molecule mimetics as potential therapeutic agents for neurodegeneration and neuroinflammation” T. Calogeropoulou 

Posters

• 09-10.09.2021 | Virtual | UNICAEN 
  EFMC-YMSC 2021, 8th EFMC Young Medicinal Chemists’ Symposium.
  Mirjana Antonijevic (ESR6), poster presentation
  
  
• 29.08 - 02.09.2021 | Virtual | UNICAEN 
  EFM-ISMC 2021, XXVI EFMC International Symposium on Medicinal Chemistry. Poster presentation by Mirjana Antonijevic (ESR6).
  
  
• 02-03.03.2021 | Virtual | UNICAEN
  RSCPoster Twitter conference
  Poster presentation on “Design and Synthesis of the first multi-target neurotrophin mimetics, a new strategy in the battle against neurodegenerative disorders” Mirjana Antonijevic (ESR6).
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• 22-23.03.2021 | Online | NHRF
  Synthesis in Drug Discovery and Development Virtual Symposium
  ”Synthesis of new DHEA 17-spyro-cyclopropyl derivatives with Neurotrophic, Neuroprotective and Anti-Inflammatory activity” Flash poster presentation by Alessia Latorrata (ESR2)
  
  
• 14.12.2020 | UNISI PhD day | UNISI
  Federica Carucci (ESR5) contributed to the UNISI PhD day with a EuroNeurotrophin poster.
  
  
• 11.12.2020 | 3rd one MNDA Symposium | USFD
  Marco Destro (ESR14) gave a poster presentation entitled “The neuroprotective effects of neurotrophins in novel in vitro and in vivo models of Motor Neurone Disease (MND/ALS)”.
  
  
• 22.-25.09.2020 | Virtual | UNISI
  GeCry School, Federica Carucci (ESR5) presented her 1-page Fiche summarizing her individual research project within EuroNeurotrophin.
   
  
• 7.-11.09.2020 | Virtual | UNICAEN
  EFMC-ISMC & EFMC-YMCS 2020, Mirjana Antonijević (ESR6) contributed to the Virtual Poster Sessions with a EuroNeurotrophin poster.
   
  
• 30.06.2020  | Sheffield Medical School | USFD
  2nd Year USFD Med School, Marco Destro (ESR14) gave a poster presentation entitled “The neuroprotective effects of neurotrophins novel in vitro and in vivo models of Motor Neurone Disease (MND/ALS)”.
  
  
• 29.-30.04.2020 | Virtual | UNICAEN
  Symposium on “Advanced therapies in Neurodegeneration: Bridging Neuroscience, Bioengineering and Optogenetics” Poster presentation by Mirjana Antonijević (ESR6).
  
  
• 04.03.2020 | HITS gGmbH | HITS
  Athanasios-Alexandros Tsengenes (ESR3) and Christina Athanasiou (ESR4) presented their work in the EuroNeurotrophin project in a joint poster session with the Molecular Biomechanics and Computational Carbon Chemistry groups of HITS.
  
  
• 20.-21.02.2020 | Fiesole, IT | UNISI
  1st AIC-BMM Group Meeting, Federica Carucci (ESR5) presented her 1-page Fiche summarizing her individual research project within EuroNeurotrophin.
  
  
• 29.- 31.01.2020 | Caen, FR | UNICAEN
  27th YRFM -Young Research Fellows Meeting During the 3 day event, Mirjana Antonijević (ESR6) contributed with a poster presentation which won an award for best flash poster.
  
  
• 21-23.08.2019 | Nottingham, UK | UNICAEN
  27th Annual GP2A Medicinal Chemistry Conference
  “In silico screening and development of small molecules neurotrophin receptors ligands” Mirjana Antonijević (ESR6) received best poster award
  
  
• 20-22.02.2019 | Paris, FR | UNICAEN
  YRFM -Young Research Fellows Meeting, Annual meeting organised by UNICAEN
  “In silico screening and Hit to lead development of small molecules neurotrophin receptors ligands” Mirjana Antonijević (ESR6)
  
  
• 14-16.10.2019 | FORTH Patras, EL | FORTH
  FORTH Retreat, 12th FORTH Scientific Retreat organised by FORTH
  "Identifying novel neurotrophin analogs: from structural interventions to biological selectivity to promote neuroprotection and neurogenesis" Thanasis Rogdakis (ESR11), Despoina Charou (ESR12), A. Gravanis
  
  
• 22-24.07.2019 | Kloster Schöntal, DE | HITS
  DKFZ-ZMBH alliance retreat
  - “Computer-Aided Drug Design of Small-Moleculeneurotrophin Mimetics” Athanasios-Alexandros Tsengenes (ESR3)
  - “Simulations of the TrkA Receptor to Elucidate the Mechanism of Action of Neurotrophin Mimetics” Christina Athanasiou (ESR4)
  
  
• 07-10.05.2019 | Heraklion, EL | UNICAEN
  EMBO Workshop Cell biology of the neuron: Polarity, plasticity and regeneration
  
  
• 05-06.09.2019 | Zappeion Conference & Exhibition Center, Athens, EL | NHRF, HITS
  EFMC-YSMC’19, 6th EFMC Young Medicinal Chemist Symposium, Conference poster presentations by
  - “Design and Synthesis of Dehydroepiandrosterone-Based Neurotrophinmimetics” Daniele Narducci (ESR1)
  - “Synthesis and biological evaluation of dehydroepiandrosterone 17-spiro-cyclopropyl derivatives with neurotrophin and neuroprotective activity” Alessia Latorrata (ESR2) won poster prize
  - “Computer-Aided Drug Design of Small-Moleculeneurotrophin Mimetics” Athanasios-Alexandros Tsengenes (ESR3)
  - “Simulations of the TrkA Receptor to Elucidate the Mechanism of Action of Neurotrophin Mimetics” Christina Athanasiou (ESR4)
  
  
• 05.07.2019 | Caen, FR | UNICAEN
  Normandy Doctoral School of Chemistry Day
  ” Identification and development of small molecules neurotrophin receptors ligands” Mirjana Antonijević (ESR6)
  
  
• 04-06.10.2019 | IMBB – FORTH, EL, FORTH
  28th meeting of the Hellenic Society of Neuroscience
  "Identifying novel neuro-trophin analogs: from structural interventions to biologi-cal selectivity to promote neuroprotection and neuro-genesis" Thanasis Rogdakis (ESR11), Despoina Charou (ESR12), A. Gravanis .
  
  
• 01-05.09.2019 | Peniche, PT | NKUA
  XVI International Symposium on Marine Natural Products, XI European Conference on Marine Natural Products
  "Marine-derived microorganisms as potential sources of neurotrophin mimetics for the tratment of neurodegeneretion and neuroinflammation" Paolo Giaccio (ESR7)
  
  
• 01-05.09.2019 | Zappeion Conference & Exhibition Center, Athens, EL | NHRF, HITS
  EFMC-ASMC'19, 8th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
  - “Design and Synthesis of Dehydroepiandrosterone-Based Neurotrophinmimetics” Daniele Narducci (ESR1)
  - “Synthesis and biological evaluation of dehydroepiandrosterone 17-spiro-cyclopropyl derivatives with neurotrophin and neuroprotective activity” Alessia Latorrata (ESR2)
  - “Computer-Aided Drug Design of Small-Moleculeneurotrophin Mimetics” Athanasios-Alexandros Tsengenes (ESR3)
  - “Simulations of the TrkA Receptor to Elucidate the Mechanism of Action of Neurotrophin Mimetics” Christina Athanasiou (ESR4)

EuroNeurotrophin Press Release

ESR Fiches