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      • ESR1: Daniele Narducci
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EURONEUROTROPHIN
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      • ESR6: Mirjana Antonijević
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      • ESR8: Canelif Yilmaz
      • ESR9: Ana Aragón
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      • ESR11: Thanasis Rogdakis
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      • ESR13: Evangelia Thanou
      • ESR14: Marco Destro
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Prof. Christophe Rochais

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B4: Université de Caen Normandie, France
Université de Caen Normandie, UFR des Sciences Pharmaceutiques, Centre d'Etudes et de Recherche sur le  médicament de Normandie, CERMN
Position
Professor of Organic Chemistry, CERMN, Faculty of Pharmacy, Health Department, University of Caen Normandy

Background
Christophe Rochais received his PhD in the group or Prof. S. Rault from the University of Caen Basse-Normandie (2005). After a post-doctoral fellowship that he completed in the Centre for Biomolecular Sciences of the University of Nottingham under the supervision of Pr Peter M. Fischer, he was appointed Lecturer in Organic Chemistry in the Faculty of Pharmacy at the University of Caen Normandy in 2007 and since January 2014 he assumed the position of Professor in Organic Chemistry. His research interests include medicinal chemistry program in the field of enzymatic inhibition and receptor modulation in order to develop pharmacological tools and bioactive compounds. Since 2012 he is leading an research program dedicated to the development of pleiotropic agents of interest in the treatment of Alzheimer's disease.

Role in EuroNeurotrophin
Main Supervisor ESR 6
Work Package Leader WP1 Design, Synthesis and Isolation from Marine Microorganisms of Small Molecule Mimetics of Neurotrophins

Key Publications
  • Jourdan, J.-P.; Since, M.; El Kihel, L.; Lecoutey, C.; Corvaisier, S.; Legay, R.; Sopkova-de Oliveira Santos, J.; Cresteil, T.; Malzert-Fréon, A.; Rochais, C.; Dallemagne, P. Benzylphenylpyrrolizinones with Anti-Amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer’s Disease Treatment. ChemMedChem 2017, 12, 913–916.
  • Lalut, J.; Tournier, B. B.; Cailly, T.; Lecoutey, C.; Corvaisier, S.; Davis, A.; Ballandonne, C.; Since, M.; Millet, P.; Fabis, F.; Dallemagne, P.; Rochais, C. Synthesis and Evaluation of Novel Serotonin 4 Receptor Radiotracers for Single Photon Emission Computed Tomography. Eur. J. Med. Chem. 2016, 116, 90–101.
  • Rochais, C.; Lecoutey, C.; Gaven, F.; Giannoni, P.; Hamidouche, K.; Hedou, D.; Dubost, E.; Genest, D.; Yahiaoui, S.; Freret, T.; Bouet, V.; Dauphin, F.; Sopkova de Oliveira Santos, J.; Ballandonne, C.; Corvaisier, S.; Malzert-Fréon, A.; Legay, R.; Boulouard, M.; Claeysen, S.; Dallemagne, P. Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT4R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride. J. Med. Chem. 2015, 58, 3172–3187.
  • Lecoutey, C.; Hedou, D.; Freret, T.; Giannoni, P.; Gaven, F.; Since, M.; Bouet, V.; Ballandonne, C.; Corvaisier, S.; Malzert-Fréon, A.; Mignani, S.; Cresteil, T.; Boulouard, M.; Claeysen, S.; Rochais, C.; Dallemagne, P. Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment. Proc. Natl. Acad. Sci. USA 2014, 111, E3825–E3830.
View Christophe Rochais's ORCID profile for a full list of publications
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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 765704
Disclaimer | Member Area
© accelopment Schweiz 2019. ALL RIGHTS RESERVED.
  • Project
    • Overview
    • Research >
      • Work Packages
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    • Governance
  • Network
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  • People
    • Supervisors >
      • Theodora Calogeropoulou
      • Rebecca Wade
      • Stefano Mangani
      • Christophe Rochais
      • Vasileios Roussis
      • Vasileia Ismini Alexaki
      • Achilleas Gravanis
      • Ka Wan Li
      • Dame Pamela Shaw
    • Early Stage Researchers >
      • ESR1: Daniele Narducci
      • ESR2: Alessia Latorrata
      • ESR3: Athanasios-Alexandros Tsengenes
      • ESR4: Christina Athanasiou
      • ESR5: Federica Carucci
      • ESR6: Mirjana Antonijević
      • ESR7: Paolo Giaccio
      • ESR8: Canelif Yilmaz
      • ESR9: Ana Aragón
      • ESR10: Débora Pita
      • ESR11: Thanasis Rogdakis
      • ESR12: Desponia Charou
      • ESR13: Evangelia Thanou
      • ESR14: Marco Destro
    • Scientific Advisory Board
  • Training
    • Approach
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    • Events >
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      • 3rd Network Week
  • Publications
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    • Events
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    • Results
    • Conference
    • Newsletter >
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  • News
  • Job Openings
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